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A Guide to Understanding ABGs

If you’re someone who struggles with ABGs, you’re not alone.

Reading the results of an Arterial Blood Gas (ABG) test takes practice and unfortunately a bit of memorization. And while that takes time, it’s a critical skill for healthcare professionals.

Blood Gases: Why?


Perhaps the best way to get started in understanding ABGs is to revisit the importance of blood gasses in general.

Arterial blood gas labs are crucial in helping us:

1. Determine the respiratory and metabolic status of a patient
2. Decide if a patient is requiring more aggressive oxygen therapy
3. Decide if our treatments are being beneficial to the patient or if other changes need to be made

ABGs are likely the most commonly used blood gas and are frequently used when assessing someone’s respiratory status. They are also an important reflection of overall pulmonary function and can help with acid-base interpretation.

Breaking Down ABG Results


First things first! When interpreting ABG results, you need to understand what’s normal.

Normal findings for an ABG include:

Index Normal Range
pH 7.35-7.45
pCO2 35-45 mm Hg
HCO3 22-26
PaO2 At least > 60 mmHg


A common challenge I hear about is remembering whether the results for the pH are an acidotic finding or an alkalotic finding.

An acidotic finding is a LOW pH (< 7.35) and an alkalotic finding is a HIGH pH (> 7.45). When the pH of the blood is outside of the normal range, by manipulating acid and base, the body tries to pull the pH back to normal.

pHs levels outside of the normal range, combined with irregular pCO2 and HCO3 levels, indicate one of four abnormalities:

1. Metabolic acidosis
2. Metabolic alkalosis
3. Respiratory acidosis
4. Respiratory alkalosis

Remember that carbon dioxide is a respiratory acid and bicarbonate is a metabolic base. This means that the lungs and the kidneys work together manipulating acid and base to try and pull the pH back to normal.

Remembering what each of these abnormalities mean (and what it can be caused by) can be another area of confusion.

Refer to this table for a quick reminder:

Cyndi Graph
The next natural question is often “Why? Why is the patient experiencing an abnormal ABG?”

Common causes of abnormal ABG findings are a main topic in my comprehensive online class, Demystifying Lab Values from Head to Toe.

Broken into six advanced sessions, this intensive course will provide you with step–by–step instruction on lab tests using a review of systems, then include why these labs are typically ordered, the pathophysiology behind abnormal values, and an understanding of what types of symptoms your patient will experience as the values either deteriorate or improve.

You’ll end the training with the ability to look beyond the numbers to putting the pieces of the puzzle together. This will allow you a better understand what is happening, why it is happening, and when you need to be concerned.

Enroll now and receive over 60% off. 7.9 CE hours are included in the course tuition.

Demystifying Lab Values
Unless you are working directly in a lab, you have most likely had no formal training regarding lab work. This is a huge issue because you need to fully understand what is happening with your patient.

This online course teaches you to look not just at the numbers, but beyond them to finally understand what is happening, why it is happening, and when you need to be concerned.
Cyndi Zarbano MSN-Ed, CCRN, CMSRN, LNC
Cyndi Zarbano, MSN-Ed CCRN, CMSRN, LNC, brings 30 years of frontline nursing experience across intensive care, emergency, and flight nursing – and she continues to take patient assignments as an intensive care nurse at Mayo Clinic in Minnesota. That direct patient care isn’t just background; it’s the foundation of everything she teaches.

A sought-after speaker on national and international stages, Cyndi is known for delivering evidence-based clinical content with the kind of real-world perspective and genuine humor that makes learning stick. She practices what she preaches when it comes to professional growth, currently pursuing her third master’s degree – this one in leadership.

Her expertise extends well beyond the bedside. Since 2008, Cyndi has served as a legal nurse consultant on more than 200 cases spanning plaintiff, defense, and boards of nursing matters. She has accumulated critical perspectives on clinical documentation, standards of care, and the moments when nursing judgment makes all the difference. A 10-year US Navy veteran who left service as a Lieutenant Commander, she carries that same precision, discipline, and commitment to excellence into every room she enters.

 

Speaker Disclosures:
Financial: Cynthia Zarbano is the owner of Clinical Review Consultants and has an employment relationship with Mayo Mankato. She receives a speaking honorarium, recording, and book royalties from PESI, Inc. She has no relevant financial relationships with ineligible organizations.
Non-financial: Cynthia Zarbano has no relevant non-financial relationships.

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