Novel and Not So Novel Anticoagulants
Mechanism of Action, Indications for Clinical Use and Therapeutic Monitoring
- Speaker:
- Paul Langlois, APN, PhD, CCRN, CCNS
- Duration:
- 2 Hours 06 Minutes
- Format:
- Audio and Video
- Copyright:
-
Mar 24, 2022
- Product Code:
- POS078431
- Media Type:
- Digital Seminar
Description
Options for anticoagulation have been expanding steadily over the past few decades, providing a greater number of agents for prevention and management of thromboembolic disease. In addition to heparins and vitamin K antagonists, anticoagulants that directly target the enzymatic activity of thrombin and factor Xa have been developed. Appropriate use of these agents requires knowledge of their individual characteristics, risks, and benefits.
In this recording, we highlight with clinical case studies and pharmacodynamic data the practical aspects of the use of direct thrombin inhibitors (oral and parenteral) and oral direct factor Xa inhibitors, along with other anticoagulants in development (medications which target the active form of factor XI and monoclonal antibody Blocking factor XI).
Indications and efficacy of anticoagulants in specific clinical settings and under clinical conditions are presented. Moreover, management of bleeding and perioperative management of patients receiving direct thrombin inhibitors and direct factor Xa inhibitors will also be discussed.
Credit
Handouts/Brochure
| File type | File name | Number of pages | |
|---|---|---|---|
| Manual - Novel and Not So Novel Anticoagulants (5.5 MB) | 98 Pages | Available after Purchase | |
| Transcript - Novel and Not So Novel Anticoagulants (198.7 KB) | 32 Pages | Available after Purchase | |
| Manual - Novel and Not So Novel Anticoagulants - French (5.5 MB) | 98 Pages | Available after Purchase | |
| Transcript - Novel and Not So Novel Anticoagulants - French (198.7 KB) | 32 Pages | Available after Purchase | |
| Manual - Novel and Not So Novel Anticoagulants - Italian (5.5 MB) | 98 Pages | Available after Purchase | |
| Transcript - Novel and Not So Novel Anticoagulants - Italian (198.7 KB) | 32 Pages | Available after Purchase | |
| Manual - Novel and Not So Novel Anticoagulants - German (5.5 MB) | 98 Pages | Available after Purchase | |
| Transcript - Novel and Not So Novel Anticoagulants - German (198.7 KB) | 32 Pages | Available after Purchase | |
| Manual - Novel and Not So Novel Anticoagulants - Spanish (5.5 MB) | 98 Pages | Available after Purchase | |
| Transcript - Novel and Not So Novel Anticoagulants - Spanish (198.7 KB) | 32 Pages | Available after Purchase |
Speaker
Paul Langlois, APN, PhD, CCRN, CCNS Related seminars and products
Paul Langlois, APN, PhD, CCRN, CCNS, is a critical care clinical specialist in the surgical, medical, neurologic, burn, CCU, and trauma ICUs of Cook County Hospital, Chicago. Drawing on over 40 years of experience assessing and managing patients with life-threatening diseases, Dr. Langlois provides advanced-level training to nurses, physician assistants, nurse practitioners, respiratory therapists, and physicians.
Dr. Langlois is committed to providing the highest quality of care to patients through advanced education. His presentations are evidence-based, timely, and provide participants with numerous case studies to facilitate critical thinking. As a bedside clinical nurse specialist, he has developed several institution-wide protocols for the multidisciplinary assessment and management of infectious disease and multi-system organ failure patients.
His presentations are enthusiastically delivered and offer highly practical tips that help make the most challenging concepts easy to understand. Linking knowledge to clinical practice is the goal of every educational program.
Speaker Disclosures:
Financial: Dr. Paul Langlois has employment relationship with Cook County Hospital and Emergency Care Consultants. He receives a speaking honorarium and recording royalties from PESI, Inc. He has no relevant financial relationships with ineligible organizations.
Non-financial: Dr. Paul Langlois is a member of the American Nurses Association, the American Association of Critical Care Nurses, and the Society of Critical Care Medicine.
Additional Info
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Objectives
- Analyze the mechanism of action of vitamin K antagonists.
- Distinguish three clinical conditions when anticoagulation is indicated.
- Evaluate contraindications when prescribing anticoagulant medications.
- Assess therapeutic range for three laboratory tests to monitor anticoagulants.
Outline
Unfractionated Heparin- Mechanism of action
- Dosing
- Laboratory monitoring
- Reversal agent
- Limited indications for laboratory monitoring
- Renal Adjustment
- Mechanism of action on the clotting cascade
- Monitoring parameters
- Contraindications for use
- Reversal agents
- Mechanism of action
- Clinical conditions for use
- Reversal agent
- Standard dosing
- Indications for treating clinical conditions
- Prophylactic dosing
Medications Which Effect Actions of Anticoagulants
- P-Glycoprotein inhibitors and inducers
- Cytochrome P-450 inhibitors and inducers
- Aspirin
- Non-steroidal anti-inflammatory drugs
Contraindications for Anticoagulation
Case Studies
Target Audience
- Nurses
- Nurse Practitioners
- Physicians
- Physicians Assistants
Reviews
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